Oct 25, 2024
Exploring the Efficacy of Autologous Platelet Leukocyte Rich Plasma Injections in Chronic Low Back Pain & Understanding Degenerative Lumbar Spinal Stenosis
Host David Rosenblum, MD
Episode Date: October 25, 2024
In this episode, Dr. David Rosenblum discusses two significant studies related to chronic low back pain and degenerative lumbar conditions. The first study focuses on the use of autologous platelet leukocyte rich plasma (PLRP) injections for treating atrophied lumbar multifidus muscles, while the second study investigates the correlation between muscle atrophy and the severity of degenerative lumbar spinal stenosis (DLSS).
Featured Article 1:
- Effect of Autologous Platelet Leukocyte Rich Plasma Injections on
Atrophied Lumbar Multifidus Muscle in Low Back Pain Patients with
Monosegmental Degenerative Disc Disease
- **Authors:** Mohamed Hussein, Tamer Hussein
Key Points Discussed
1. Background: Correlation between lumbar multifidus muscle
dysfunction and chronic low back pain.
2. Study Overview: 115 patients treated with weekly PLRP
injections for six weeks, followed for 24 months.
3. Outcome Measures: Significant improvements
in NRS and ODI scores, with high patient satisfaction.
4. Conclusions: PLRP injections into the atrophied multifidus
muscle are safe and effective for managing chronic low back
pain.
Featured Article 2:
- Degenerative Lumbar Spinal Stenosis
Authors:* Gen Xia, Xueru Li, Yanbing Shang, Bin Fu,
Feng Jiang, Huan Liu, Yongdong Qiao
Key Points Discussed
1. Background: DLSS is a common condition in older adults,
often leading to muscle atrophy and disability.
2. Study Overview: A retrospective analysis involving 232 patients
to investigate the correlation between muscle atrophy and spinal
stenosis severity.
3. Results:
- Significant differences in the ratio of fat-free
multifidus muscle cross-sectional area between stenotic and
non-stenotic segments.
- A strong positive correlation was found between
multifidus atrophy and the severity of spinal stenosis.
- The atrophy was more pronounced on symptomatic sides
of the spine compared to contralateral sides.
4. Conclusions: The findings suggest that more severe
spinal stenosis is associated with greater muscle atrophy,
emphasizing the importance of addressing muscle health in DLSS
patients.
Discussion:
Dr. Rosenblum provides insights into how these studies inform
clinical practices for treating chronic low back pain and managing
degenerative conditions. He emphasizes the need for comprehensive
treatment strategies that consider both muscle health and spinal
integrity which may be achieved via peripheral nerve stimulation of
the medial branch nerve and multifidus muscle or PRP injection in
to the multifidus muscle.
Closing Remarks:
Listeners are encouraged to stay informed about innovative
treatment options and the importance of muscle assessment in
managing spinal disorders.
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**Disclaimer:** The information presented in this podcast is for educational purposes only and should not be considered medical advice. Always consult a healthcare professional for medical concerns.
References